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Complement C4mg/dL

Complement C4 is an immune system protein that, like C3, falls when the immune system is actively consuming it.

See your own Complement C4 on its range.

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What Complement C4 measures

Complement C4 is an immune system protein that, like C3, falls when the immune system is actively consuming it.

If your Complement C4 is low

C4 below the range is commonly associated with active complement consumption, as in lupus, or with an inherited low level; it is also low in hereditary angioedema.

Commonly associated with

Worth asking your clinician: How C3 and the autoimmune panel look.

If your Complement C4 is high

C4 above the range is commonly associated with inflammation or infection.

Commonly associated with

Worth asking your clinician: Whether other inflammation markers are raised.

Typical reference range

GroupTypical range
Adults10 – 40 mg/dL

Typical adult values used by many US labs. Your own report prints the range your lab validated for its method, and that range is the one that counts. Labwise always uses the printed range first.

If it is within range

Your complement C4 is within the range printed by your lab.

Also listed as

C4, C4 Complement, Complement Component 4, C4, Serum

Related tests

This page is general information about what a laboratory test measures and what results outside a reference range are commonly associated with. It is not medical advice, does not diagnose any condition and does not replace your clinician. Discuss your results with your healthcare provider.