Labwise

LabwiseTestsVitamins

Methylmalonic Acidnmol/L

Methylmalonic acid rises when cells lack usable vitamin B12. It is a more sensitive check of B12 status than the B12 level alone.

See your own Methylmalonic Acid on its range.

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What Methylmalonic Acid measures

Methylmalonic acid rises when cells lack usable vitamin B12. It is a more sensitive check of B12 status than the B12 level alone.

If your Methylmalonic Acid is low

A low methylmalonic acid is not usually a concern and is commonly seen with good B12 status.

Commonly associated with

Worth asking your clinician: Nothing specific; this side of the range is rarely meaningful.

If your Methylmalonic Acid is high

Methylmalonic acid above the range is commonly associated with low vitamin B12 in the tissues, even when the B12 level itself looks acceptable; kidney function can also raise it.

Commonly associated with

Worth asking your clinician: Whether B12 supplementation or absorption testing is being considered.

Typical reference range

GroupTypical range
Adults0 – 378 nmol/L

Typical adult values used by many US labs. Your own report prints the range your lab validated for its method, and that range is the one that counts. Labwise always uses the printed range first.

If it is within range

Your methylmalonic acid is within the range printed by your lab, which is commonly read as adequate B12 at the tissue level.

Also listed as

MMA, Methylmalonic Acid, Serum, Methylmalonic Acid, Plasma

Related tests

This page is general information about what a laboratory test measures and what results outside a reference range are commonly associated with. It is not medical advice, does not diagnose any condition and does not replace your clinician. Discuss your results with your healthcare provider.